Now showing items 1-8 of 8

    • Winter, José Luis; Castro, Pablo F.; Quintana, Juan Carlos; Altamirano, Rodrigo; Enriquez, Andrés; Verdejo, Hugo E.; Jalil Milad, Jorge; Mellado, Rose Marie; Concepción, Roberto; Sepúlveda, Pablo; Rossel Mariángel, Víctor; Sepúlveda Morales, Luis; Chiong Lay, Mario; García Nannig, Lorena; Lavandero González, Sergio (Elsevier, 2014)
      Objectives: Heart failure (HF) is associated with changes in myocardial metabolism that lead to impairment of contractile function. Trimetazidine (TMZ) modulates cardiac energetic efficiency and improves outcomes in ...
    • Rossel Mariángel, Víctor; Díaz Toro, Felipe; Verdejo, Hugo; Concepción, Roberto; Sepúlveda, Luis; Castro, Pablo; Vukasovic, José Luis; Bernales, Angie; Bernales, Angie (Sociedad Medica de Santiago, 2017)
      Background: Galectin-3 (Gal-3) is a mediator of myocardial fibrosis involved in cardiac remodeling and a potential new prognosis marker in heart failure (HF). Aim: To measure Gal-3 at the moment of discharge in patients ...
    • Greig, Douglas; Castro, Pablo; Gabrielli, Luigi A.; Miranda, Rodrigo; Verdejo, Hugo; Alcaíno Gálvez, Hernán Alejandro; Bustos, Carlos; Chiong Lay, Mario; Godoy, Iván; Mellado, Rose Marie; García Nannig, Lorena; Salas, Daniela; Vivar Sánchez, Raúl; Vukasovic Ramírez, José Luis; Concepción, Roberto; Díaz Araya, Guillermo (SOC MEDICA SANTIAGO, 2008-06)
      Background: In chronic heart failure (CHF), endothelial dysfunction (ED) is a consequence of an imbalance of vascular tone regulating substances. The relationship between ED and inflammation has not been fully investigated. ...
    • Castro, Pablo; Gabrielli, Luigi A.; Verdejo, Hugo; Greig, Douglas; Mellado, Rose Marie; Concepción, Roberto; Sepúlveda Morales, Luis; Vukasovic Ramírez, José Luis; García Nannig, Lorena; Pizarro, Marcela; Pivet, Deisy; Carrillo, Constanza; Tapia, Fabiola; Navarro, Mario; Troncoso, Rodrigo; Baraona, Fernando; Llevaneras, Silvana; Hernández, Claudia; Godoy, Iván; Jalil Milad, Jorge; Quintana, Juan Carlos; Orellana, Pilar; Chiong Lay, Mario; Lavandero González, Sergio (SOC MEDICA SANTIAGO, 2010-08)
      It is unknown why heart failure progresses even when patients are treated with the best therapy available. Evidences suggest that heart failure progression is due to loss of neurohumoral blockade in advanced stages of the ...
    • Miranda, Rodrigo; Castro, Pablo; Verdejo, Hugo; Chiong Lay, Mario; Díaz Araya, Guillermo; Mellado, Rose Marie; Rojas, Diego; Concepción, Roberto; Lavandero González, Sergio (SOC MEDICA SANTIAGO, 2007-08)
      Despite advances in treatment, chronic heart failure still is associated with a pool- prognosis and remains a leading cause of cardiovascular death. Cumulatingi evidence sugigest,; that imbalances in redox state lead to a ...
    • Castro, Pablo; Winter, José Luis; Verdejo, Hugo; Orellana, Pilar; Quintana, Juan Carlos; Greig, Douglas; Enríquez, Andrés; Sepúlveda, Luis; Concepción, Roberto; Sepúlveda, Pablo; Rossel Mariángel, Víctor; Chiong Lay, Mario; García Nannig, Lorena; Lavandero González, Sergio (2012)
      Background Ventricular dyssynchrony is a common finding in patients with heart failure (HF), especially in the presence of conduction delays. The loss of ventricular synchrony leads to progressive impairment of contractile ...
    • Alcaíno Gálvez, Hernán Alejandro; Greig, Douglas; Chiong Lay, Mario; Verdejo, Hugo; Miranda, Rodrigo; Concepción, Roberto; Vukasovic Ramírez, José Luis; Díaz Araya, Guillermo; Mellado, Rose Marie; García Nannig, Lorena; Salas, Daniela; González, Leticia; Godoy, Iván; Castro, Pablo; Lavandero González, Sergio (ELSEVIER, 2008-07)
      Increased serum uric acid has been identified as an independent risk factor for cardiovascular disease. However, because of its antioxidant capacity, uric acid may play a beneficial role in endothelial function. This ...
    • Meyer, Lital; Concepción, Roberto; Zamorano, Nibaldo; Armstrong, Macarena; Castro, Leonardo; Mujica, Maximiliano; Asenjo, René (SOC MEDICA SANTIAGO, 2012-02)
      Tachycardiomyopathy is a potentially reversible cause of heart failure. It can be induced by supraventricular or ventricular arrhythmias. When these are treated, systolic function improves or normalizes. We report a 20 ...